Anti-cholinergi and antimicrobial properties of mangrove plant avicennia lanata

Abstract

Avicennia lanata is commonly known as grey mangroves or white mangroves which classified in the family of A vicenniaceae. Several researches were conducted on its closely related species Avicennia marina but there is no or few being carried out on A. lanata. The leaf, bark and root part of this plant has been extracted sequentially using dichloromethane, ethyl acetate and methanol respectively. Each of the extracts is tested for its anti-cholinergic and antimicrobial properties. Two major active compounds (phenols/tannins and saponins) were observed in the root extracts which also contained glycosides and freeze dried leaf extract with alkaloid compounds. The highest anticholinesterase (AchE) enzyme activity is showed by freeze dried leaf extract with 86.22% of AchE enzyme inhibition then followed with 73.37% and 71.73% from methanol root extract and ethyl acetate root extract respectively at concentration of 2.5µg/ml.