Anti-cholinergic and anti-microbial properties of ceriops tagal (Temu)

Abstract

Finding natural antimicrobial compounds with minimum side effects on health is important due to increasing numbers of antibiotic-resistant strains. Although there is currently no cure for Alzheimer's disease (AD), new treatments are on the horizon as a result of accelerating insight into the biology of the disease. Mangrove plants have extensively been used in medicinal fields. In the present study, the leaves and roots of Ceriops tagal were prepared by using 3 different solvents including: dichloromethane, ethyl acetate and methanol sequentially. This study aimed to determine the antimicrobial, phytochemical screening and also anticholinesterase properties by using the mangrove plants. Antimicrobial activities were tested against five antibiotic-resistant and pathogenic bacteria which are Bacillus cereus, Staphylococcus aureus, Salmonella typhii, Escherichia coli and Klebsiella pneumonia by using the disc-diffusion and micro dilution assay. Results showed that the methanol extract had the best results while the dichloromethane extract appeared weaker in both disc diffusion and micro dilution assay.