Anti-cholinergic and antimicrobial properties of sonneratia alba (perepat)

Abstract

Plants have been widely used as the medicine because of their medicinal value. In this study, we used two assays to identify the medicinal value that contained in mangrove plant Sonneratia alba. The antimicrobial activity of leaf and bark extract of S.alba in three different solvent such as dichloromethane, ethyl acetate and methanol was determine by using two in vitro model, disc diffusion assays and minimum inhibitory concentration (MIC) assays against five species of pathogenic bacteria such as Staphylococcus aureus, Klebsiella pnuemoniae, Salmonella typhii, Escherichia coli, and Bacillus cereus. In disc diffusion method, freeze dried leaf methanol extract was show the highest inhibition zone that others with 1.45±0.15 mg/ml against Staphylococcus aureus.