Abstract:
The antibacterial, antibiofilm and antioxidant activities of sponge collected from
Bidong Island were investigated. Marine environment is a rich source of bioactive
compounds so do sponges. Methanol extracts of Ircinia sp. were test for antibacterial
against gram positive and gram negative bacteria, antibiofilm and antioxidant. Ircinia
sp. was inactive against the eight strains bacteria and do not show any inhibition area
when test for antibacterial. This is due to the compound contain in this genus do not
active. Only control, Gentamycin and Ampicilin showed inhibitory against these
bacteria. For antibiofilm, the compounds contain in this genus induce the biofilm
formation and can be said the compounds only showed antibiofilm at low
concentration. Whereas for antioxidant, this genus shows some oxidation activity but
lower than the control, quercetin and also lower than IC5o. The highest percent
inhibition is 46.1539 % at 5mg/mL.
