Bioactivities in marine sponge, ircinia sp. from Bidong Island

Abstract

The antibacterial, antibiofilm and antioxidant activities of sponge collected from Bidong Island were investigated. Marine environment is a rich source of bioactive compounds so do sponges. Methanol extracts of Ircinia sp. were test for antibacterial against gram positive and gram negative bacteria, antibiofilm and antioxidant. Ircinia sp. was inactive against the eight strains bacteria and do not show any inhibition area when test for antibacterial. This is due to the compound contain in this genus do not active. Only control, Gentamycin and Ampicilin showed inhibitory against these bacteria. For antibiofilm, the compounds contain in this genus induce the biofilm formation and can be said the compounds only showed antibiofilm at low concentration. Whereas for antioxidant, this genus shows some oxidation activity but lower than the control, quercetin and also lower than IC5o. The highest percent inhibition is 46.1539 % at 5mg/mL.