Anti-microbial and anti-oxidant activity of proteinaceous extract from acanthaster planci

Abstract

Echinoderms are known as one of the sources that able to produce large variety of novel bioactive compounds. COT starfish Acanthaster planci has numerous kinds of protein or peptide which can possess wide of variety of biological activities. The objectives of this study were to isolate proteinaceous extract from A. planci and to evaluate anti-microbial and anti-oxidants activity of isolated protein from A. planci. The starfish A. planci was collected from Pulau Bidong. Its body and spine part was extracted with phosphate buffer solution and ethanol. The anti-microbial activity was tested agaisnt pathogenic bacterial by using well-diffusion method. The anti-oxidant activity also be tested by using 2, 2-diphenyl-1-picrylhydrazyl (DPPH) scavenging assay.