Synthesis and characterization of substituted-benzoylthiourea valine and theoreonine derivatives

Abstract

Study of benzoylthiourea derivatives has received immense attentions from researchers worldwide due to their versatility in many fields. Owing to the great potentials they offered, therefore, this research project was carried out. In this study, twenty substituted-benzoylthiourea amino acid have been successfully synthesized and characterized using FT-IR spectroscopy, UV-Vis spectrophotometer, NMR spectroscopy and Mass Spectrometry. To be specific, sixteen new compounds have been obtained, while four compounds have been previously reported. Compound 4-MeOBTT was obtained as single crystal and it has been further characterized by Single Crystal X-Ray Crystallography.