Abstract:
Acute Hepatopancreatic Necrosis Disease (AHPND), a disease caused by
Vibrio parahaemolyticus (VPAHPND), rest:.lts in mass mortalities worldwide in the
Penaeid shrimp aquacultme industry, leading to severe fmanciallosses. To understand
the immunity response of Penaeus monodon post-larvae (PL) towards VpAHPND
infection, the shrimp survivability, expression of immunity genes and presence of
bacterial toxin genes were investigated and validated in three stages of P. monodon PL
(PL15, PL30 and PL45). In a total of20-hom time-course challenge test conducted for
the PL stages that were exposed to 2.7 x 10
7
cfu ml-
1
ofVpAHPND, highest mortality was
observed in PL 30 (81 %), followed by PL15 (65%) and PL45 (1.67%).