dc.contributor.author |
Siti Nor Khadijah Addis |
|
dc.date.accessioned |
2012-07-24T03:18:23Z |
|
dc.date.available |
2012-07-24T03:18:23Z |
|
dc.date.issued |
2011-11 |
|
dc.identifier.uri |
http://hdl.handle.net/123456789/1653 |
|
dc.description.abstract |
Flaviviruses are a group of positive-strand RNA viruses of global significance. The
flavivirus RNA genome encodes a single open reading frame that is directly translated into a single polyprotein and cleaved by host and virally encoded
proteases prior to protein maturation. Hence, the proteolytic cleavage events play a central role in the process of viral gene expression in flaviviruses. Despite the importance of these events, the mechanism of proteolytic cleavage leading to the generation of the two non-structural proteins, NS1 and NS2A is poorly defined. |
en_US |
dc.language.iso |
en |
en_US |
dc.publisher |
Australian national University |
en_US |
dc.relation.ispartofseries |
;QP 609 .P78 S5 2011 |
|
dc.subject |
QP 609 .P78 S5 2011 |
en_US |
dc.subject |
Siti Nor Khadijah Addis |
en_US |
dc.subject |
Tesis The Australian National University 2011 |
en_US |
dc.subject |
Proteolytic enzymes |
en_US |
dc.title |
Genetic and functional analysis of the proteolytic cleavage at the junction of the NS1 and NS2a proteins of murray valley encephalitis virus |
en_US |
dc.type |
Thesis |
en_US |