Characterization and mechanistic studies on the synthesis of 1,3,4-thiadiazole derivatives

Abstract

The versatile compound of thiourea and a highly biological potential of Sbenzyldithiocarbazate (SBDTC) compound have inspired the production of hybrid compounds which contained both moieties which are thiourea and dithiocarbazate. For this reason, a reaction between acyl chloride, ammonium thiocyanate and SBDTC were reacted to produce the desired thiourea-dithiocarbazate derivatives. However, the desired compound did not obtained from the reaction but gives a heterocyclic compound namely 1,3,4-thiadiazole derivatives.