Inactivated form of hemocyanin subunit from Malaysian horseshoe crab tachypleus gigas as potential antimicrobial agent

Abstract

Hemocyanin is abundantly found in the hemolymph of the horseshoe crab Tachypleus gigas. Its vital roles are to serve as an oxygen transporter and defensive protein. However, it is believed that inactivated form of hemocyanin has antimicrobial properties as does its analogue, phenoloxidase. Therefore, this research was carried out to compare the antimicrobial response towards the hemocyanin in inactivated form and activated hemocyanin (phenoloxidase).