Cytotoxicity effects and cell death mechanisms of avicennia alba and bruguiera gymnorrhiza extracts on human breast cancer cell line (MCF-7)

Abstract

Breast cancer is the second leading cause of cancer death and the most common form of cancer affecting women worldwide. Currently. over 50% of drugs used in clinical trials for cancer treatments were isolated from natural sources. Hence, the search for natural products to be used in cancer therapy represents an area of great interest in which the plant kingdom has been the most important source, providing man) anti-tumor agents with novel structures and unique mechanism of action.