Phytochemical screening of Chromolaena odarata (L.) extracts for anti-bacterial, anti oxidant and anti-leukaemic properties

Abstract

Chromolaena odorata (L.) is a noxious weed that can be found spreading widely in tropical countries. Traditionally, this plant was used to cure wounds and minor burns. The polyphenolic compounds in the crude extract and terpenoids compounds in the essential oil of Chromolaena odorata were found to be responsible in inhibiting bacterial and HL 60 cells (Human Promyelocytic Leukaemia) growth. In addition, it also showed the potential as anti-oxidant agent. The content of Chromolaena odorata crude extract that contain polyphenol compounds was determined using LC-MS, whereas the compositions of the essential oil that contain terpenoid compounds were obtained using GC-MS.