The effect of extracts from free-living amoebae on pathogenic bacteria

Abstract

The effect of amoeba extracts from two species of amoebae Acanthamoeba AK and Acanthamoeba Pl , was studied on a pathogenic bacteria Staphylococcus aureus. The amoebae used in this study were Acanthamoeba P 1, isolated from marine environment and Acanthamoeba AK, a clinical isolate. The amoeba extracts at different concentrations, which were 4.5 mg/ml, 9.0 mg/ml and 18.0 mg/ml were tested on Staphylococcus aureus. All the extracts used, showed the anti-bacterial activities indicating that these extracts do have potential to be used as anti-bacterial agents, due to the MIC value, Pl extract have more potential values compared to AK extract because from the observation, the inhibition percentage of bacteria colony in treatment with Pl were decrease obviously.