The role of membrane surface charge on properties and the performances of polymeric membranes for protein application

Abstract

Ultrafiltration has become an alternative technology for protein separation over conventional bioseparation processes because of its high throughput of product. Although ultrafiltration is a useful method for protein separation,it is prone to biofouling. Fouling can be reduced by using membranes with suitable charge to the solute being filtered and this could also allow selective separation. A study to investigate the role of membrane surface charge and the influence of different polymer concentration on ultrafiltration membrane performance for protein separation has been performed.