Abstract:
The important of this study is to discover a novel antibiotic for pharmaceuticals from few
species of exclusive mangroves. The aims of this study are to determine the mangrove
plants that having antibacterial activity, determine the minimal inhibitory concentration
(MIC) of extract and to determine the plants which highest antibacterial activities. The
methanolic extract of old leaves from one species of Pteridaceae; Acrosthicum aureum
and four species of Rhizophoraceae; Bruguiera gymnorrhica, B. sexangula, Ceriops
decantra and Rhizophora apiculata collected from Setiu Wetland and around Universiti
Malaysia Terengganu were tested for antibacterial activities against seven pathogenic
bacteria which are three Gram positive; Staphylococcus aureus, Micrococcus sp and
Bacillus subtilis and four Gram negative; Pseudomonas aeruginosa, Escherichia coli,
Klebsiella pneumonia and Vibrio fischeri. The disc diffusion test was used in this project.
The methanolic extract of all the species in Rhizophoraceae family showed the
antibacterial activity against all the Gram positive bacteria and no antibacterial activity in
the Gram negative bacteria. C. decantra showed the lowest MIC value on B. subtilis at
I OOµg/ml and was the only plant with the most broad spectrum activity and showed the
highest antibacterial activities against all the bacteria tested. It can be concluded that the
plants with the lowest MIC value could be a good source of bioactive components with
antibacterial potency.
