Abstract:
Natural product research is guided by bioactivity test. Herbal plants especially
Capsicum frutescens (Family: Solanaceae) is rich sources of bioactive compounds
were commonly used as medicinal and therapeutic purposes. The aims of this study
were to determine the toxicity effect of C. frutescens and to compare the different
toxicity effect of fruit and leaf extracts of C. frutescens on third instar of Aedes
aegypti larvae. Fruit and leaf extracts were extracted using 98.99% of methanol
solvent and were tested on Ae. aegypti larvae in different concentrations which were
0.25 mg/ml, 0.5 mg/ml, 1 mg/ml, 2 mg/ml and 4 mg/ml. Bioassays test exposure was
done for 24 hours. The results obtained showed that LC50 value for fruits and leaves
extract were 1.2692 mg/ml and 1.3929 mg/ml, respectively (P>0.05: paired t-test).
There were no significant differences for both extracts of C. frutescens as P=
0.621 was more than 0.05. These show that both parts of extracts C. frutescens produced
compounds and could be useful for a template of synthetic insecticides.
