Abstract:
An antibiotic is one class of antimicrobials that can potentially be used as medical
drugs to treat infections. Resistance to antibiotic today is so extensive that some of the
first generation of antibiotics is of no utilize anymore. Thus antibacterial resistance is
presently a vital focus of research and new antibiotics are needed to fight these
pathogens. Thus this study was carried out to find potential another antibiotic from
bacteria isolated from forest soil that can contribute to our good health. Soil samples
were obtained from four forests which are Hutan Lipur Jambu Bangkok, Hutan Pecah
Rotan, Bukit Nenasi and Forest Soil in Tanah Merah. A total of 52 isolated bacteria
from soil samples were obtained using serial dilutions and pour plate method. The
capability of antibiotic production of the isolated bacteria was determined using
Antagonist Method and Disc Diffusion Test. There are eight isolated bacteria found to
show antimicrobial activity with different size of inhibition zones. The isolated
bacteria in this study were named as Isolate A, B, C, D, E, F, G and H. These bacteria
can be manipulated further to test against other pathogenic microorganisms.
