Abstract:
MCF-7 cells are human breast cancer cells, the second most common types of cancer
that cause death among women. The significance of this study is to investigate the
potential of extracts of amoebae as anti-cancer agent. Previous study conducted by
Iliana (2005) showed that the number of CEM-SS cells was decreased after treated
with Acanthamoeba lysates. In other study, Acanthamoeba was found to contain
proteolytic enzymes which caused the degradation of extracellular components of
corneal cells. In the present study, lysates of two Acanthamoeba species namely
Acanthamoeba sp. (SW) and Acanthamoeba castellanii (IMR) were treated in vitro on
MCF-7 cells line.
