Abstract:
Marine actinomycete isolated from Bidong Island seawater was screened for
antimicrobial activities against a panel of selected bacteria and fungi. Positive results
against yeast Saccharomyces cerevisiae, gram-positive of Streptococcus agalactiae,
Staphylococcus aureus and Bacillus subtillis and gram-negative of Klebsiella
pneumonia, Pasteurella multocida except Aeromonas hydrophila and Escherichia coli
were noted. Determination of optimal temperature and salinity for the growth of
marine actinomycete cultured artificially in the laboratory was done and followed by
antimicrobial susceptibility testing on target S. agalactiae. The best group of marine
actinomycete in terms of secondary metabolites production was the one cultured at
27°C with O ppt salinity. The optimized growth however was from the culture
condition at 37°C with O ppt which suggested the possibility of terrestrial origin.
Correlation is significant, in which salinity and temperature showed moderate and
high correlation (r = -0.641 and 0.734) respectively with marked relationship towards
the dependant values of marine actinomycete growth. [The growth of marine
actinomycete affected by temperature and salinity using this fundamental testing of
measuring diameter colonies was significant (p<0.01)]. The results showed the ability
of marine actinomycete to produce antimicrobial activities and its potential as an
antimicrobial agent from marine resource. The people who involve in antimicrobial
research should undertake the findings forward especially in determining the
actual/definite strength of this species against different types of target microbes.
